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antibacterial drug

Laboratory：Hachioji

○antibacterial drug

TEST NAME	SPECIMEN REQUIREMENT （ｍL）	CONTAINER	CAP COLOR	STORE TEMPERATURE (STABILITY)	TURNAROUND TIME (DAY)	METHODOLOGY	REFERENCE RANGE (UNIT)	BLOOD COLLECTION TIME
Amikacin	serum 0.4	S7P ↓ A00			2-4	EIA Enzyme immunoassay (EIA) EIA is based on the same assay principle as RIA. Using either enzyme-labeled antigen or antibody as a labeledsubstance, the antigen-antibody reaction is carried out. After adding a chromogenic substrate, the enzyme activity is measured.	Peak: 50-60 Trough: < 4 (μg/mL) See below	1 hour after the start of infusion (30minutes after the completion of infusion if given for 30minute
Tobramycin	serum 0.4	S7P ↓ A00			2-4	EIA Enzyme immunoassay (EIA) EIA is based on the same assay principle as RIA. Using either enzyme-labeled antigen or antibody as a labeledsubstance, the antigen-antibody reaction is carried out. After adding a chromogenic substrate, the enzyme activity is measured.	Peak: 15-20 Trough: < 1 (μg/mL) See below	1 hour after the start of infusion (30minutes after the completion of infusion if given for 30minute
Gentamicin	serum 0.4	S7P ↓ A00			2-4	EIA Enzyme immunoassay (EIA) EIA is based on the same assay principle as RIA. Using either enzyme-labeled antigen or antibody as a labeledsubstance, the antigen-antibody reaction is carried out. After adding a chromogenic substrate, the enzyme activity is measured.	Peak: 15-20 Trough: < 1 (μg/mL) See below	1 hour after the start of infusion (30minutes after the completion of infusion if given for 30minute
Arbekacin	serum 0.3	S7P ↓ A00		（21 days）	2-4	Latex agglutination immunoassay Latex agglutination immunoassay (LA) Using antigen- or antibody-coated latex particles, the antigen-antibody reaction is carried out. The turbidity of clots formed by the antigen-antibody reaction is measured by the light transmittancy or light scattering intensity.	Peak: 15-20 Trough: < 1 (μg/mL)	1 hour after the start of infusion (30minutes after the completion of infusion if given for 30minute
Vancomycin	serum 0.4	S7P ↓ A00			2-4	EIA Enzyme immunoassay (EIA) EIA is based on the same assay principle as RIA. Using either enzyme-labeled antigen or antibody as a labeledsubstance, the antigen-antibody reaction is carried out. After adding a chromogenic substrate, the enzyme activity is measured.	Trough 10-15 (μg/mL)	Within 30minutes before administration(Trough concentration)
Teicoplanin	serum 0.3	S7P ↓ A00			2-4	Latex agglutination immunoassay Latex agglutination immunoassay (LA) Using antigen- or antibody-coated latex particles, the antigen-antibody reaction is carried out. The turbidity of clots formed by the antigen-antibody reaction is measured by the light transmittancy or light scattering intensity.	Trough 15-30 (μg/mL)	Within 30minutes before administration(Trough concentration)
Voriconazole	plasma 0.3	PH5 ↓ A00			3-5	LC/MS/MS Liquid chromatography-tandem mass spectrometry (LC/MS/MS) Liquid chromatography separates the target substance into compounds using difference in the affinity, which is combined with the mass spectrometry function that further divides the compounds by mass difference to isolate, fragment, and detect a specific mass ion.	(μg/mL)