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antibacterial drug

Laboratory：Hachioji

○antibacterial drug

TEST NAME	SPECIMEN REQUIREMENT （ｍL）	CONTAINER	CAP COLOR	STORE TEMPERATURE (STABILITY)	TURNAROUND TIME (DAY)	METHODOLOGY	REFERENCE RANGE (UNIT)	BLOOD COLLECTION TIME
Amikacin	Serum 0.4	S7P ↓ A00			2-4	KIMS KIMS (Kinetic Interaction of Microparticles in Solution) A method in which an antigen-antibody reaction is performed using microparticles bound to antigens or antibodies, and the turbidity of the agglutination caused by the antigen-antibody reaction is measured from the transmittance by irradiating it with light.	Peak 50-60 Trough Less than 4 (μg/mL) See below	1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Peak concentration) Within 30 minutes before administration (Trough concentration)
Tobramycin	Serum 0.4	S7P ↓ A00			2-4	Enzyme immunoassay(EIA) EIA (Enzyme immunoassay) Enzyme immunoassay The measurement principle is the same as RIA; an antigen-antibody reaction is performed using an enzyme-labeled antigen or antibody as a labeling substance, and a chromogenic substrate is added to detect enzyme activity. How to measure.	Peak 15-20 Trough less than 1 (μg/mL) See below	1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Peak concentration) Within 30 minutes before administration (Trough concentration)
Gentamicin	Serum 0.4	S7P ↓ A00			2-4	Enzyme immunoassay(EIA) EIA (Enzyme immunoassay) Enzyme immunoassay The measurement principle is the same as RIA; an antigen-antibody reaction is performed using an enzyme-labeled antigen or antibody as a labeling substance, and a chromogenic substrate is added to detect enzyme activity. How to measure.	Peak 15-20 Trough less than 1 (μg/mL) See below	1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Peak concentration) Within 30 minutes before administration (Trough concentration)
Arbekacine	Serum 0.3	S7P ↓ A00		（21 days）	2-4	Latex agglutination turbidimetry LA (Latex agglutination immunoassay) Latex agglutination turbidimetry An antigen-antibody reaction is performed using latex particles that have adsorbed (bound) antigens or antibodies, and the turbidity of the agglutination caused by the antigen-antibody reaction is measured using light. A method of measuring from transmittance or scattering intensity of light by irradiation.	Peak 15-20 Trough Less than 1-2 (μg/mL)	1 hour after the start of the infusion (30 minutes after the end if administered in 30 minutes) (Peak concentration) Within 30 minutes before administration (Trough concentration)
Vancomycin	Serum 0.4	S7P ↓ A00			2-4	Latex agglutination turbidimetry LA (Latex agglutination immunoassay) Latex agglutination turbidimetry An antigen-antibody reaction is performed using latex particles that have adsorbed (bound) antigens or antibodies, and the turbidity of the agglutination caused by the antigen-antibody reaction is measured using light. A method of measuring from transmittance or scattering intensity of light by irradiation.	Trough10-15(μg/mL)	Within 30 minutes before administration (Trough concentration)
Teicoplanin	Serum 0.3	S7P ↓ A00			2-4	Latex agglutination turbidimetry LA (Latex agglutination immunoassay) Latex agglutination turbidimetry An antigen-antibody reaction is performed using latex particles that have adsorbed (bound) antigens or antibodies, and the turbidity of the agglutination caused by the antigen-antibody reaction is measured using light. A method of measuring from transmittance or scattering intensity of light by irradiation.	Trough15-30(μg/mL)	Within 30 minutes before administration (Trough concentration)
Voriconazole	Plasma 0.3	PH5 ↓ A00			3-5	LC/MS/MS LC/MS/MS (Liquid chromatography tandem mass spectrometry) Liquid chromatography tandem quadrupole mass spectrometry Liquid chromatography uses differences in affinity to decompose components of a target substance. , a method in which ions of a specific mass are further separated by mass using a mass spectrometer, dissociated and fragmented, and then these ions are detected.	(μg/mL)