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chromosomal test
chromosomal test for solid tumors

Laboratory：Hachioji

○chromosomal test for solid tumors

TEST NAME	SPECIMEN REQUIREMENT （ｍL）	CONTAINER	CAP COLOR	STORE TEMPERATURE (STABILITY)	TURNAROUND TIME (DAY)	METHODOLOGY	REFERENCE RANGE (UNIT)
1p Deletion	tissues 5×5×5mm	H00			7-10	FISH Fluorescence in situ hybridization (FISH) The target DNA is hybridized with a fluorescent probe. Using a light with a specific wavelength, the fluorescent site in the chromosome is detected as a signal by fluorescence microscope. The direct method uses a fluorescent probe to directly bind to the target DNA. The indirect method uses a labeled probe to bind to the target DNA which is subsequently bound to a fluorescence substance for color development.
MYCN 2p24 amplification	tissues 5×5×5mm	H00			7-10	FISH Fluorescence in situ hybridization (FISH) The target DNA is hybridized with a fluorescent probe. Using a light with a specific wavelength, the fluorescent site in the chromosome is detected as a signal by fluorescence microscope. The direct method uses a fluorescent probe to directly bind to the target DNA. The indirect method uses a labeled probe to bind to the target DNA which is subsequently bound to a fluorescence substance for color development.
MYCN 2p24 amplification	bone marrow fluid 1.0	H00			7-10	FISH Fluorescence in situ hybridization (FISH) The target DNA is hybridized with a fluorescent probe. Using a light with a specific wavelength, the fluorescent site in the chromosome is detected as a signal by fluorescence microscope. The direct method uses a fluorescent probe to directly bind to the target DNA. The indirect method uses a labeled probe to bind to the target DNA which is subsequently bound to a fluorescence substance for color development.
19q Deletion	tissues 5×5×5mm	H00			7-10	FISH Fluorescence in situ hybridization (FISH) The target DNA is hybridized with a fluorescent probe. Using a light with a specific wavelength, the fluorescent site in the chromosome is detected as a signal by fluorescence microscope. The direct method uses a fluorescent probe to directly bind to the target DNA. The indirect method uses a labeled probe to bind to the target DNA which is subsequently bound to a fluorescence substance for color development.
EWSR1 22q12 translocation	tissues 5×5×5mm	H00			7-10	FISH Fluorescence in situ hybridization (FISH) The target DNA is hybridized with a fluorescent probe. Using a light with a specific wavelength, the fluorescent site in the chromosome is detected as a signal by fluorescence microscope. The direct method uses a fluorescent probe to directly bind to the target DNA. The indirect method uses a labeled probe to bind to the target DNA which is subsequently bound to a fluorescence substance for color development.
EWSR1 22q12 translocation	bone marrow fluid 1.0	H00			7-10	FISH Fluorescence in situ hybridization (FISH) The target DNA is hybridized with a fluorescent probe. Using a light with a specific wavelength, the fluorescent site in the chromosome is detected as a signal by fluorescence microscope. The direct method uses a fluorescent probe to directly bind to the target DNA. The indirect method uses a labeled probe to bind to the target DNA which is subsequently bound to a fluorescence substance for color development.