Laboratory：Hachioji
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- antiepileptic drug
- Nitrazepam
Laboratory：Hachioji
○Nitrazepam
CODE：0841 9
-
TEST NAME
SPECIMEN
REQUIREMENT
（ｍL） CONTAINER CAP COLOR STORE
TEMPERATURE
(STABILITY) TURNAROUND
TIME (DAY) METHODOLOGY REFERENCE RANGE
(UNIT) BLOOD COLLECTION TIME -
Nitrazepam
Serum
0.3
S7P
↓
A00
3-5 LC/MS/MS20～200(ng/mL) Immediately before the next administration (Trough concentration) However, when used as an antiepileptic drugLC/MS/MS (Liquid chromatography tandem mass spectrometry)
Liquid chromatography tandem quadrupole mass spectrometry
Liquid chromatography uses differences in affinity to decompose components of a target substance. , a method in which ions of a specific mass are further separated by mass using a mass spectrometer, dissociated and fragmented, and then these ions are detected.
COMMENT
Benzalin,
Nelbon
Points to note concerning blood collecting containers
Avoid using a container with a serum separating agent. It may effect the results on the drug tests.
Points to note concerning the blood collecting time
1. The blood collecting time is for TDM (therapeutic drug monitoring).
2. In repetitive administration, collect a blood sample after a steady state is achieved.
3. When poisoning is developed, the peak concentration also needs to be measured.
4. The blood collecting time shows the standard time: a patient's condition should be taken into account in collecting a blood sample.
CONTAINER
S7P 旧容器記号 C4 X2 X1
分離剤なし (真空採血量7mL)
貯蔵方法：室温
有効期間：製造から1年
A00 旧容器記号 X
ポリスピッツ
貯蔵方法：室温
